12.05.2025 | Tracker
Respiratory Tracker: Lung Cancer: The most discussed respiratory condition by HCPs this quarter
Throughout January-March 2025, CREATION Pinpoint® tracked the conversations of UK online healthcare professionals (HCPs) discussing respiratory diseases on X (Twitter). We analysed 2,956 posts discussing respiratory diseases by 966 HCPs.

This quarter, lung cancer accounted for 18% of the total online respiratory HCP discussions. A total of 154 HCPs contributed to the conversation, each posting an average of 3.5 times on the topic. This level of activity was notably higher than the average number of posts per author seen within the top 5 respiratory disease discussions this quarter: COVID-19 (2.4 posts per author), asthma (2.0), RSV (1.9), and pneumonia (1.7).
You mean ANOTHER big year for lung cancer! The pace of chance and new treatment data is huge. Several other practice changing trials due to report later this year- given what we know from press releases and FDA breakthrough designation/priority reviews- so do watch this space.
— Sanjay Popat (@DrSanjayPopat) January 8, 2025
The conversation spanned a wide range of themes, from vaccine innovations, awareness about lung cancer in women, to the environmental impact causing lung cancer. Notably, there was a strong focus on clinical advances, especially in relation to non-small cell lung cancer (NSCLC). Our analysis uncovered 197 NSCLC HCP mentions.
What an amazing presentation on Lung Cancer and Young Women from @NarjustFlorezMD on the @ests_womenThor & @IASLC webinar!@Florez_Lab and #HearHer campaign to increase awareness about lung cancer in women is terrific! pic.twitter.com/mtJP9yVvB0
— Cecilia Pompili MD PhD FACS (@pompili_cecilia) January 29, 2025
The third big win for CAN-2409 in 3 months!
Candel Therapeutics reports both markedly prolonged median overall survival and a long tail of survival in phase 2a clinical trial of CAN-2409 in advanced non-small cell lung cancer (NSCLC) patients non-responsive to immune checkpoint…
— Dr. Paul Peter Tak (@paulpetertak) March 27, 2025
A key driver in the lung cancer-related conversation was The British Thoracic Oncology Group (BTOG25) conference in Belfast; a significant event in the UK lung cancer calendar. Mentions of the event led to a 900% increase in lung cancer discussions. HCPs frequently used the hashtag #BTOG25, making it the second most used hashtag across all respiratory-related posts this quarter.
Nice simple overview of peri-operative strategies for patients with resectable/operable NSCLC at #BTOG25 from surgical colleagues. pic.twitter.com/Z0tvegIdop
— Crispin Hiley (@crispinhiley) March 4, 2025
Great talk by @HoudaBahig on role of RT in stage3 NSCLC. Boy, you’ve got a tough tumor board #BTOG25 @BTOGORG @DotorJSpicer pic.twitter.com/E8oOrcAtLw
— Sanjay Popat (@DrSanjayPopat) March 4, 2025
During the conference, HCPs shared insights from various sessions, including discussions around reducing toxicity from lung cancer therapy and the potential gaps between clinical best practice and national treatment guidelines. The event also served as a platform for HCPs to amplify the latest developments in lung cancer care; 68% of these mentions were reshares.
Awesome radiotherapy symposia at #BTOG25 including stellar talks from @HoudaBahig @Mat_Guc & @MatthewEvison1
My overall take-home:
non-RT factors have never been more important for unravelling the toxicity that restricts how we expand our application of RT in lung cancer! pic.twitter.com/4Gps168Jnj— Gerard Walls (@gwalls89) March 3, 2025
Excited to present our @royalmarsdenNHS cohort analysis on the efficacy of the use of tepotinib in NSCLC patients with a MET exon 14 skipping mutation or amplification at #btog25 @BTOGORG Come check it out at #105 poster booth 🫁🩺🩻🔬⚕️💊 pic.twitter.com/WhxX10Lmku
— Foteini Kalofonou (@FKalofonou) March 3, 2025
In addition to BTOG25, the European Lung Cancer Congress (ELCC 2025) was another pivotal moment in the lung cancer conversation. HCPs highlighted several treatment innovations showcased during the conference. For instance, Oncologist Crispin Hiley reflected on the increasing complexity of treatment pathways for EGFR mutation-positive NSCLC, noting that while this presents challenges, it is ultimately a reflection of progress.
Slick discussion of complexity post Osimertinib decision making for patients with EGFR mutation positive NSCLC by @stephanieplsaw – it’s a good problem to have in 2025 #LCSM #ELCC25 pic.twitter.com/APQBgo484v
— Crispin Hiley (@crispinhiley) March 26, 2025
Among the most discussed trials were COCOON, MARIPOSA, and FLAURA2; all of which explored new combinations and strategies aimed at improving patient outcomes. Oncologist Giannis Mountzios emphasized the critical importance of ongoing clinical research, not only to enhance efficacy but also to refine and personalise treatment strategies based on “genetic and clinical risk factors.”
An excellent debate here in #ELCC25 on the optimal choice for 1st Line treatment of EGFR pos #NSCLC :
⭐️. Osimertinib monotherapy VS
Combinations (FLAURA2/MARIPOSA)
Insightful lectures by @ZPiotrowskaMD and @APassaroMD focusing on efficacy endpoints, biology, toxicity and… pic.twitter.com/ugf8xpFS6D
— Giannis Mountzios (@g_mountzios) March 27, 2025
Furthermore, Johnson & Johnson’s positive results from the MARIPOSA trial were well received by several HCPs. Thoracic medical oncologist Adam Januszewski highlighted the “great data” as potentially “practice-changing.”
Overall Survival data for Mariposa – use of Ami and Laz in 1L EGFR mutant lung cancer. Great data … practice changing??
HR 0.75 (95% CI 0.61-0.92) Osimertinib 36.7 months vs not reached for Amivantamab + lazertinib
Can we manage toxicities to maintain QoL?#ELCC2025 pic.twitter.com/AZ8CMliFGF
— Dr Adam Januszewski (@AdamJanuszewski) March 26, 2025
Osimertinib BEATEN!! MARIPOSA (Ami + Lazer) shows significant OS (HR 0.75, p<0.005, 3yr 60% vs 51%) and landmark 3-yr icPFS improvement (36% vs 18%)—first combo to show OS superiority over SoC, extending OS beyond 3 years in 1L EGFRm NSCLC. #ESMOAmbassadors #ELCC25 @myESMO pic.twitter.com/cstBfz89iS
— Noemi Reguart (@NReguart) March 26, 2025
Beyond lung cancer discussions, HCPs also raised awareness around the asthma crisis in the UK, with many focusing on paediatric asthma. A total of 251 HCPs contributed to the conversation, collectively reaching over 3 million accounts. Posts amplified campaigns and initiatives calling for improved respiratory health policies. For instance, Professor Nick Hopkinson supported Asthma + Lung UK’s call for the government to take lung health seriously. Nurse Sara Nelson highlighted the use of NHS data to improve air quality, while Respiratory nurse Kate Lippiett shared updates on NIHR research into new approaches to support children and young people with asthma.
Tragically after 60 years preventable asthma deaths continue in childhood in the UK where one child dies every month from asthma in England. Please share this podcast with those caring for children. Apple: https://t.co/gkthS2wg9f Spotify: https://t.co/ftTnVFMG82 pic.twitter.com/NGDCpD8XYy
— Dr Mark L Levy (@bigcatdoc) February 4, 2025
Moreover, in the RSV conversation, HCPs shared recent data indicating that the RSV vaccine has led to a notable decrease in hospital admissions among older adults. HCPs advocated for vaccination as crucial in preventing severe illness; Professor of Cancer Virology, Stephen Griffin, amplified a post calling for enhanced infection control measures in health social care settings.
Early data from @P_H_S_Official show that RSV vaccination (@pfizer ABRYSVO) in older adults aged 75-79 was associated with 62% ⬇️ (95%CI 35-80%) in #RSV hospitalisation. 🦠🏥💉👏
Vaccination commenced mid August 2024 & uptake was 68.6% (end of Nov 2024).https://t.co/XCecaXNEoO https://t.co/JW0OjXaWop pic.twitter.com/J89ztK0wyV
— Antonia Ho (@DrToniHo) February 14, 2025
RSV vaccine massively reduced hospital stay in my home country Scotland 🏴
Vaccines work! https://t.co/jzHcBRulof
— Neil Stone (@DrNeilStone) February 14, 2025
Additionally, 61 HCPs shared developments in the UK’s vaping/smoking regulation and research, including the Tobacco and Vapes Bill and a new government study on vaping’s long-term effects on children. HCPs also highlighted the rise of lung cancer in never-smokers and the importance of integrating smoking cessation services.
Cannabidiol #vaping is not likely safe.
Case report in @JTOonline of multifocal #NSCLC #lungcancer associated with excessive vaping in a 24-year old female. https://t.co/000RQ4QaiC
— Gerry Hanna (@gerryhanna) February 27, 2025
Why is there an increase in lung #cancer among #women who have never smoked? https://t.co/8tuE2Oh250 About 2.5 million new lung cancer cases were diagnosed worldwide in 2022 – an increase of 300,000 since 2020. The study suggests that #environmental factors, particularly air…
— Dr. Aliya Shah (@aliya_Hshah) February 13, 2025
Each month, we track the HCP conversation relating to respiratory disease. You can read other editions in the Respiratory Tracker archive .
You can also keep updated with other pharmaceutical tracking updates, including how HCPs engage with Top 50 pharma and the product approvals that are catching their attention. To receive updates straight to your inbox you can sign up for our monthly eJournal with our latest HCP insights.
If you want to dig deeper into what we have seen this month then please get in touch.
Methodology
- CREATION Pinpoint® was used to analyse 2,956 mentions on X from 966 HCPs in the UK discussing respiratory disease and related terms, throughout January-March 2025.